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Reviews in Oncology

Functional imaging with diffusion and perfusion MRI in the evaluation of the response to CHT-RT therapy in head and neck cancer

Review, 21 - 28
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Abstract
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Background oropharyngeal squamous cell carcinomas (HNSCCs) have shown a significant increase in incidence. Currently, non image based clinical outcome metrics include morphology, clinical, and laboratory parameters. An imaging biomarker that would provide for an early quantitative metric of clinical treatment response in these cancer patients would provide for a paradigm shift in cancer care.
Method we selected and evaluated 24 original researches and 9 systematic reviews focused on the utility of dynamic contrast enhanced (DCE) and diffusion-weighted imaging (DWI) MR in cancer imaging.
Aim by discussing the current status of these advanced neuro imaging techniques the goal of this study is to evaluate the possibility of DCE- and DWIMRI in the assessment of the functional aspects of tumor physiology pertaining to their application in
the prognosis and monitoring of treatment response in tumors arising in the head and neck region.

Vol. 3 (No. 1) 2015 January - December

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  1. Functional imaging with diffusion and perfusion MRI in the evaluation of the response to CHT-RT therapy in head and neck cancer
    Piludu F., Guerrisi A., Izzo G., Marzi S., Vidiri A.
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